Donald married Ann McMillan on 16 Mar 1827 in Strontian, Argyll, Scotland. Ann (daughter of Archibald MacMillan and Cathrine Campbell) was born on 6 Mar 1805 in Scotstoun, Strontian, Argyll, Scotland; died on 12 Jan 1890 in Scotstoun, Strontian, Argyll, Scotland. [Group Sheet]

1. Archibald McPherson was born on 10 Jul 1827 in Aharacle, Argyll, Scotland; and died.
2. Sarah McPherson was born about 1832 in Scotstoun, Argyll, Scotland; and died.
3. Alexander McPherson was born about 1833 in Scotstoun, Argyll, Scotland; and died.
4. Donald McPherson was born about 1837 in Scotstoun, Argyll, Scotland; died on 10 Jun 1887 in Glasgow, Lanarkshire, Scotland.
5. Ann McPherson was born about 1838 in Scotstoun, Argyll, Scotland; and died.
6. Ewen McPherson was born on 5 Oct 1839 in Aharacle, Argyll, Scotland; and died.
7. John McPherson was born about 1844 in Scotstoun, Argyll, Scotland; and died.
8. Catherine McPherson was born about 1846 in Scotstoun, Argyll, Scotland; and died.
9. Duncan McPherson was born about 1849 in Scotstoun, Argyll, Scotland; died on 5 May 1930 in Strontian, Argyll, Scotland.