Family: James O'Brien / Jane MacIsaac (F952)
 | Archibald MacIsaac (1801-1880) |
 | Mary MacMaster (1806-1882) |
| Margaret MacIsaac (1831-1911)  |
| Mary MacIsaac (1835-1919) |
| Kate MacIsaac (1836- ) |
| John MacIsaac (1841- ) |
| Donald MacIsaac (1842-1907) |
| Mary Ann MacIsaac (1846- ) |
| Flora MacIsaac (1848- ) |
| Jane MacIsaac (1852- ) 
|